Participation in a metastatic breast cancer clinical trial involves various aspects, including eligibility assessment based on specific criteria outlined in the trial protocol, detailed information provided about the trial’s purpose, procedures, potential risks, and benefits, allowing participants to make an informed decision about participation, administration of the investigational treatment or therapy as outlined in the trial protocol, regular follow-up visits and assessments to monitor treatment response, disease progression, and potential side effects and access to a multidisciplinary team of healthcare professionals who provide medical care, support, and guidance throughout the trial.