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Prurigo Nodularis Clinical Trials in Oklahoma City, OK

Hightower is conducting Prurigo Nodularis Clinical Trials to evaluate the effectiveness of an investigational treatment.

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Persistent Itches and Tough Skin Nodules Due to Prurigo Nodularis?

Prurigo Nodularis causes intense itches, and firm nodules on the skin, leading to significant discomfort and distress. It affects approximately 72 per 100,000 individuals, with many patients experiencing long-lasting or recurrent symptoms. The condition is often resistant to topical treatments, making it difficult to manage effectively.

At Hightower, we are dedicated to advancing the understanding and treatment of Prurigo Nodularis. Through our innovative Prurigo Nodularis Clinical Trials, we aim to explore new potential therapies and improve the quality of life for those affected by this debilitating condition.

*Participation in the Clinical Trial is completely free of cost and is your choice.

*To participate, fill out the form, and someone from our research staff will call you to determine your eligibility for the Clinical Research Study.

Study Information

Prurigo Nodularis

Study NameProtocol NumberSponsor
Prurigo Nodularis

20230053

Amgen

About the Study

This Prurigo Nodularis Clinical Trial will focus on the efficacy, safety, and tolerability of an investigational treatment. The study will compare the investigational drug to a placebo, looking at patient-reported outcomes like pruritus (itching) and overall clinical assessments. Participants who have not found relief through topical treatments or are not eligible for them can now contribute to groundbreaking research.

By joining these Prurigo Nodularis Clinical Trials, participants will play a vital role in helping to develop better prurigo nodularis treatments. The study will take place over 52 weeks, with close monitoring of patients throughout the process to ensure safety and effectiveness.

*All study procedures and study-related treatment, including the investigational drug, are free of cost, and insurance is not required to participate.

What to Expect

Participants in the Prurigo Nodularis Clinical Trials will be randomly assigned to either the study drug group or the placebo group. The study is double-blinded, meaning neither you nor the researchers will know which group you are in. The primary goal is to assess the reduction in itching and skin nodules over a 24-week period, with continued monitoring throughout the year.

*All study-related care is provided at no cost, with comprehensive physical exams and assessments conducted by expert physicians and healthcare professionals. *

Age

18 Years to 100 Years (Adult, Older Adult)

Gender

Male & Female

Condition

Prurigo Nodularis

Current Status

Recruiting

Understanding and Managing Prurigo Nodularis

Prurigo Nodularis can lead to both localized and systemic complications. Localized effects include the development of painful, itchy nodules on the skin, which can become infected due to excessive scratching. Systemic complications may involve emotional and psychological impacts, such as anxiety, depression, and poor sleep, due to the relentless itching and discomfort.

Common symptoms include:

  • Itchy Nodules: Firm raised bumps (nodules) on the skin that are intensely itchy.
  • Thickened Skin: The affected areas may become thicker or rough due to chronic scratching.
  • Lesions: Open sores or scabs may develop from scratching, leading to the risk of infection.
  • Redness or Dark Spots: Nodules may appear red, brown, or dark, depending on your skin tone.
  • Pain or Discomfort: Persistent itching and scratching can cause tenderness or pain around the nodules.
  • Scarring: Over time, continuous scratching and irritation can leave scars or discoloration.

Frequently Asked Questions

Can Prurigo Nodularis Spread to Other Areas of the Body?

No, Prurigo Nodularis itself does not spread from one area of the body to another. However, new nodules can develop in different areas over time, particularly in regions prone to friction or scratching. The development of additional nodules is often due to continued scratching, not the spread of the condition.

Is Prurigo Nodularis Linked to Any Underlying Health Conditions?

Yes, Prurigo Nodularis is sometimes associated with underlying health conditions such as eczema, diabetes, chronic kidney disease, or liver disease. It can also be linked to neurological or psychiatric conditions like anxiety or depression. Treating these underlying issues may help alleviate some of the symptoms of Prurigo Nodularis.

What Lifestyle Changes Can Help Reduce Prurigo Nodularis Symptoms?

Beyond medical treatments, certain lifestyle changes can help manage symptoms. These include reducing stress through relaxation techniques, avoiding hot showers that may worsen itching, maintaining a balanced diet to support skin health, and ensuring proper sleep to prevent flare-ups triggered by fatigue.

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