Adults 18 and older with refractory metastatic colorectal cancer, regardless of gender, may qualify for the study. Eligibility will be confirmed through screening by the study team.
Hightower Clinical is conducting refractory metastatic colorectal cancer clinical trials to study how often high blood pressure occurs during treatment in minority groups.
Refractory metastatic colorectal cancer (mCRC) is a form of colorectal cancer that has spread to other parts of the body and no longer responds to standard treatments. People often reach this stage after trying multiple therapies such as chemotherapy, targeted drugs or immunotherapy without seeing further improvement. It can be challenging to manage, and symptoms may continue to affect daily life as the disease progresses.
Clinical trials are currently taking place for refractory metastatic colorectal cancer, offering opportunities to contribute to advancing treatment options. If you or a loved one is facing this stage of cancer, participating in a clinical study for advanced colon cancer may offer access to potential new therapies and close monitoring from experienced clinical teams.
| Study Name | Protocol Number | Sponsor |
|---|---|---|
| Colorectal Cancer | TAK-113-4002 | Takeda |
Managing high blood pressure is an important part of care for people with refractory metastatic colorectal cancer. This colorectal cancer research study looks at how often adults from minority communities develop high blood pressure during treatment and assesses the safety of an investigational drug. The goal is to gather useful information that may guide better care in future mCRC clinical trials.
Participants receive the investigational treatment in 4-week cycles and continue as long as it works well for them. Treatment ends if their condition worsens or they decide to stop. Afterward, follow-ups every three months help monitor their health and collect meaningful data.
If you choose to participate, you’ll start by reviewing and signing an Informed Consent Form that explains the study in detail. Our research team will guide you through the process, answer your questions, and make sure you feel confident about your decision to join or withdraw at any time.
Once enrolled, you will receive the investigational treatment under close supervision. Your health will be monitored regularly through exams and evaluations by experienced physicians throughout the study.
By participating, you may contribute to the development of future treatment options for patients with refractory metastatic colorectal cancer.


18 Years and older
All
Refractory Metastatic Colorectal Cancer
Recruiting
People with refractory metastatic colorectal cancer may experience a variety of symptoms, ranging from digestive issues to overall fatigue and weakness.
Adults 18 and older with refractory metastatic colorectal cancer, regardless of gender, may qualify for the study. Eligibility will be confirmed through screening by the study team.
Participants receive the investigational treatment in 4-week cycles, undergo regular health monitoring, and follow-ups every three months. All study-related care is provided free of charge.
The study aims to understand how often high blood pressure occurs during treatment in minority communities and to assess the safety and effectiveness of the investigational drug.